|
|
L-aspartate + IMP + GTP <=> H+ + adenylosuccinate + phosphate + GDP
|
6.3.4.4
adenylosuccinate synthase
|
–
|
BMK
|
|
BRENDA:
BR141
KEGG:
R01135
MetaCyc:
ADENYLOSUCCINATE-SYNTHASE-RXN
SABIO-RK:
228
|
|
|
|
IMP + H2O <=> hypoxanthine + D-ribose_5-phosphate
|
3.2.2.1
purine nucleosidase
3.2.2.12
inosinate nucleosidase
|
–
–
|
K
|
|
BRENDA:
BR16039
KEGG:
R01128
MetaCyc:
INOSINATE-NUCLEOSIDASE-RXN
|
|
|
|
IMP + H2O <=> 5-Formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide
|
3.5.4.10
IMP cyclohydrolase
|
–
|
BMK
|
|
BRENDA:
BR19263
KEGG:
R01127
MetaCyc:
IMPCYCLOHYDROLASE-RXN
SABIO-RK:
123
|
|
|
|
H+ + AMP + H2O <=> IMP + NH3
|
3.5.4.17
adenosine-phosphate deaminase
3.5.4.4
adenosine deaminase
3.5.4.6
AMP deaminase
3.5.4.7
ADP deaminase
|
–
–
–
–
|
MK
|
|
BRENDA:
BR22743
KEGG:
R00181
MetaCyc:
AMP-DEAMINASE-RXN
SABIO-RK:
135
|
|
|
|
IMP + H2O + NAD+ <=> XMP + NADH + H+
|
1.1.1.205
IMP dehydrogenase
|
–
|
BMK
|
|
BRENDA:
BR33666
KEGG:
R01130
MetaCyc:
IMP-DEHYDROG-RXN
SABIO-RK:
128
|
|
|
|
IMP + NH3 + NADP+ <=> GMP + NADPH + H+
|
1.7.1.7
GMP reductase
|
–
|
BK
|
|
BRENDA:
BR36982
KEGG:
R01134
MetaCyc:
GMP-REDUCT-RXN
|
|
|
|
IMP + diphosphate <=> hypoxanthine + 5-phospho-alpha-D-ribose_1-diphosphate
|
2.4.2.22
xanthine phosphoribosyltransferase
2.4.2.7
adenine phosphoribosyltransferase
2.4.2.8
hypoxanthine phosphoribosyltransferase
|
–
–
–
|
BMK
|
|
BRENDA:
BR47537
KEGG:
R01132
MetaCyc:
HYPOXANPRIBOSYLTRAN-RXN
SABIO-RK:
81
|
|
|
|
Inosine + ATP <=> H+ + IMP + ADP
|
2.7.1.145
deoxynucleoside kinase
2.7.1.20
adenosine kinase
2.7.1.73
inosine kinase
2.7.1.76
2'-deoxyadenosine kinase
2.7.1.B20
|
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR47800
KEGG:
R01131
MetaCyc:
INOSINEKIN-RXN
|
|
|
|
IDP + H2O <=> IMP + phosphate + H+
|
3.6.1.5
apyrase
3.6.1.6
nucleoside diphosphate phosphatase
3.6.1.64
inosine diphosphate phosphatase
|
–
–
–
|
BK
|
|
BRENDA:
BR50469
KEGG:
R00961
MetaCyc:
RXN-14003
|
|
|
|
IMP + H2O <=> Inosine + phosphate
|
3.1.3.1
alkaline phosphatase
3.1.3.2
acid phosphatase
3.1.3.31
nucleotidase
3.1.3.5
5'-nucleotidase
3.1.3.99
IMP-specific 5'-nucleotidase
|
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR51619
KEGG:
R01126
MetaCyc:
RXN-7607
SABIO-RK:
124
|
|
|
|
ITP + H2O <=> IMP + diphosphate + H+
|
3.6.1
3.6.1.66
XTP/dITP diphosphatase
3.6.1.8
ATP diphosphatase
3.6.1.9
nucleotide diphosphatase
|
–
–
–
–
|
BK
|
|
BRENDA:
BS141249
KEGG:
R00720
MetaCyc:
RXN0-6382
SABIO-RK:
297
|
|
|
|
inosine_5''-phosphobutyrate + H2O <=> Butyrate + IMP
|
3.6.1.20
5'-acylphosphoadenosine hydrolase
|
–
|
K
|
|
BRENDA:
BS141268
KEGG:
R01690
|
|
|
|
ATP + IMP <=> ADP + IDP
|
2.7.4.3
adenylate kinase
2.7.4.8
guanylate kinase
2.7.4.9
dTMP kinase
2.7.4.B1
|
–
–
–
–
|
|
|
BRENDA:
BS358277
SABIO-RK:
9866
|
|
|
|
N6-methyladenosine_5''-monophosphate + H2O + H+ <=> IMP + methylamine
|
3.5.3
|
–
|
|
|
MetaCyc:
RXN-21583
|
|
|
|
IMP <=> IMP
|
not assigned
|
–
|
|
|
MetaCyc:
TRANS-RXN0-566
|
|
|
|
ITP + Butyrate + CoA <=> IMP + diphosphate + butyryl-CoA
|
6.2.1.2
medium-chain acyl-CoA ligase
|
–
|
|
|
BRENDA:
BS200
|
|
|
|
ITP + ferulic_acid + CoA <=> IMP + diphosphate + feruloyl-CoA
|
6.2.1.12
4-coumarate---CoA ligase
|
–
|
|
|
BRENDA:
BS30
|
|
|
|
ITP + phytanate + CoA <=> IMP + diphosphate + phytanoyl-CoA
|
6.2.1.24
phytanate---CoA ligase
|
–
|
|
|
BRENDA:
BS245
|
|
|
|
ITP + o-succinylbenzoate + CoA <=> IMP + diphosphate + 2-succinylbenzoyl-CoA
|
6.2.1.26
o-succinylbenzoate---CoA ligase
|
–
|
|
|
BRENDA:
BS363645
|
|
|
|
ITP + biotin + apo-[propionyl-CoA:carbon-dioxide_ligase_(ADP-forming)] <=> IMP + diphosphate + [propanoyl-CoA:carbon-dioxide_ligase_(ADP-forming)]
|
6.3.4.10
biotin---[propionyl-CoA-carboxylase (ATP-hydrolysing)] ligase
|
–
|
|
|
BRENDA:
BS373506
|
|
|
|
ITP + biotin + apo-[methylmalonyl-CoA:pyruvate_carboxyltransferase] <=> IMP + diphosphate + [methylmalonyl-CoA:pyruvate_carboxyltransferase]
|
6.3.4.9
biotin---[methylmalonyl-CoA-carboxytransferase] ligase
|
–
|
|
|
BRENDA:
BS743
|
|
|
|
ITP + biotin + apo-[propanoyl-CoA:carbon-dioxide_ligase_(ADP-forming)] <=> IMP + diphosphate + [propanoyl-CoA:carbon-dioxide_ligase_(ADP-forming)]
|
6.3.4.10
biotin---[propionyl-CoA-carboxylase (ATP-hydrolysing)] ligase
|
–
|
|
|
BRENDA:
BS669
|
|
|
|
5''-IMP + Inosine <=> IMP + Inosine
|
2.7.1.77
nucleoside phosphotransferase
3.1.3.5
5'-nucleotidase
|
–
–
|
|
|
BRENDA:
BS357843
|
|
|
|
3''-AMP + Inosine <=> IMP + adenosine
|
2.7.1.77
nucleoside phosphotransferase
|
–
|
|
|
BRENDA:
BS357834
|
|
|
|
ITP + D-ribose_5-phosphate <=> IMP + 5-phospho-alpha-D-ribose_1-diphosphate
|
2.7.6.1
ribose-phosphate diphosphokinase
|
–
|
|
|
BRENDA:
BS358297
|
|
|
|
(ribonucleotide)n-3''-phosphate + 5''-hydroxy-(ribonucleotide)m + ITP <=> (ribonucleotide)n+m + IMP + diphosphate
|
6.5.1.8
3'-phosphate/5'-hydroxy nucleic acid ligase
|
–
|
|
|
BRENDA:
BS444559
|
|
|
|
ITP + L-histidine + 4-aminobutanoate <=> IMP + phosphate + homocarnosine
|
6.3.2.11
carnosine synthase
|
–
|
|
|
BRENDA:
BS406
|
|
|
|
ITP + (R)-pantoate + beta-Alanine <=> IMP + diphosphate + pantothenate
|
6.3.2.1
pantoate---beta-alanine ligase (AMP-forming)
|
–
|
|
|
BRENDA:
BS399
|
|
|
|
ITP + (ribonucleotide)n + (ribonucleotide)m <=> IMP + phosphate + (ribonucleotide)n+m
|
6.5.1.3
RNA ligase (ATP)
|
–
|
|
|
BRENDA:
BS817
|
|
|
|
(ribonucleotide)10-3''-phosphate + 5''-hydroxy-(ribonucleotide)10 + ITP <=> (ribonucleotide)20 + IMP + diphosphate
|
6.5.1.8
3'-phosphate/5'-hydroxy nucleic acid ligase
|
–
|
|
|
BRENDA:
BS438570
|
|
|
|
ITP + H2O <=> IMP + phosphate
|
3.6.1.5
apyrase
3.6.1.6
nucleoside diphosphate phosphatase
|
–
–
|
|
|
BRENDA:
BS141363
|
|
|
|
IDP-ribose + H2O <=> IMP + D-ribose_5-phosphate
|
3.6.1.13
ADP-ribose diphosphatase
3.6.1.53
Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase
|
–
–
|
|
|
BRENDA:
BS141206
|
|
|
|
Phenyl_phosphate + Inosine <=> IMP + phenol
|
2.7.1.77
nucleoside phosphotransferase
|
–
|
|
|
BRENDA:
BS357909
|
|
|
|
5''-GMP + Inosine <=> IMP + guanosine
|
2.7.1.77
nucleoside phosphotransferase
|
–
|
|
|
BRENDA:
BS357839
|
|
|
|
Carbamoyl_phosphate + Inosine <=> Carbamate + IMP
|
2.7.1.77
nucleoside phosphotransferase
|
–
|
|
|
BRENDA:
BS357910
|
|
|
|
ITP + Inosine <=> IDP + IMP
|
2.7.1.B20
|
–
|
|
|
BRENDA:
BS428715
|
|
|
|
dATP + Inosine <=> dADP + IMP
|
2.7.1.73
inosine kinase
|
–
|
|
|
BRENDA:
BS357755
|
|
|
|
GTP + IMP + Ala-3-nitronate <=> GDP + phosphate + N6-(L-1-carboxy-2-nitroethyl)-AMP
|
6.3.4.4
adenylosuccinate synthase
|
–
|
|
|
BRENDA:
BS708
|
|
|
|
IMP + [phosphate]n <=> IDP + [phosphate]n-1
|
2.7.4.33
AMP-polyphosphate phosphotransferase
|
–
|
|
|
BRENDA:
BS423688
|
|
|
|
IMP + (phosphate)n+1 <=> IDP + Polyphosphate
|
2.7.4.33
AMP-polyphosphate phosphotransferase
|
–
|
|
|
BRENDA:
BS455785
|
|
|
|
IDP + H2O + a_folded_polypeptide <=> IMP + phosphate + an_unfolded_polypeptide
|
5.6.1.7
chaperonin ATPase
|
–
|
|
|
BRENDA:
BS444044
|
|
|
|
ITP + acetate + citrate_(pro-3S)-lyase <=> IMP + diphosphate + citrate(pro-3S)-lyase
|
6.2.1.22
[citrate (pro-3S)-lyase] ligase
|
–
|
|
|
BRENDA:
BS229
|
|
|
|
acetyl_phosphate + Inosine <=> acetate + IMP
|
2.7.1.77
nucleoside phosphotransferase
|
–
|
|
|
BRENDA:
BS357911
|
|
|
|
GTP + Inosine <=> GDP + IMP
|
2.7.1.B20
|
–
|
|
|
BRENDA:
BS428666
|
|
|
|
GTP + IMP <=> GDP + IDP
|
2.7.4.10
nucleoside-triphosphate---adenylate kinase
|
–
|
|
|
BRENDA:
BS379830
|
|
|
|
IMP + beta-glycinamide_ribonucleotide + H2O <=> 5-aminoimidazole-4-carboxamide_ribonucleotide + formylglycinamide_ribonucleotide
|
2.1.2.2
phosphoribosylglycinamide formyltransferase
|
–
|
|
|
BRENDA:
BS320045
|
|
|
|
CTP + Inosine <=> CDP + IMP
|
2.7.1.73
inosine kinase
2.7.1.B20
|
–
–
|
|
|
BRENDA:
BS357759
|
|
|
|
dATP + IMP <=> dAMP + inosine_3''-diphosphate_5''-phosphate
|
2.7.6.4
nucleotide diphosphokinase
|
–
|
|
|
BRENDA:
BS359837
|
|
|
|
UTP + Inosine <=> UDP + IMP
|
2.7.1.73
inosine kinase
2.7.1.B20
|
–
–
|
|
|
BRENDA:
BS357758
|
|
|
|
UTP + IMP + L-aspartate <=> UDP + phosphate + adenylosuccinate
|
6.3.4.4
adenylosuccinate synthase
|
–
|
|
|
BRENDA:
BS713
|
|
|
|
trans-alpha,beta-diformamido-beta-(5''-phosphoribosylamino)acrylamide <=> IMP + H2O
|
3.5.4.10
IMP cyclohydrolase
|
–
|
|
|
BRENDA:
BS116410
|
|
|
|
5''-IDP + H2O <=> IMP + phosphate
|
3.1.3.5
5'-nucleotidase
|
–
|
|
|
BRENDA:
BS446857
|
|
|
|
6-chloropurine_riboside_monophosphate + H2O <=> IMP + Cl-
|
3.5.4.7
ADP deaminase
|
–
|
|
|
BRENDA:
BS141112
|
|
|
|
ATP + IMP + L-aspartate <=> GDP + phosphate + adenylosuccinate
|
6.3.4.4
adenylosuccinate synthase
|
–
|
|
|
BRENDA:
BS388064
|
|
|
|
[DNA]-3''-diphospho-5''-inosine + H2O <=> [DNA]-3''-phosphate + IMP
|
3.6.1.72
DNA-3'-diphospho-5'-guanosine diphosphatase
|
–
|
|
|
BRENDA:
BS440010
|
|
|
|
4-nitrophenyl_phosphate + Inosine <=> 4-nitrophenol + IMP
|
2.7.1.77
nucleoside phosphotransferase
|
–
|
|
|
BRENDA:
BS357872
|
|
|
|
IMP + thiazole-4-carboxamide_adenine_dinucleotide + H2O <=> XMP + reduced_thiazole-4-carboxamide_adenine_dinucleotide + H+
|
1.1.1.205
IMP dehydrogenase
|
–
|
|
|
BRENDA:
BS451000
|
|
|
|
D-fructose_6-phosphate + IDP <=> D-fructose_1,6-bisphosphate + IMP
|
2.7.1.146
ADP-specific phosphofructokinase
|
–
|
|
|
BRENDA:
BS409138
|
|
|
|
5''-AMP + Inosine <=> IMP + adenosine
|
2.7.1.77
nucleoside phosphotransferase
|
–
|
|
|
BRENDA:
BS357829
|
|
|
|
ADP + Inosine <=> AMP + IMP
|
2.7.1.77
nucleoside phosphotransferase
|
–
|
|
|
BRENDA:
BS357913
|
|
|
|
ATP + IMP <=> AMP + inosine_3''-diphosphate_5''-phosphate
|
2.7.6.4
nucleotide diphosphokinase
|
–
|
|
|
BRENDA:
BS359829
|
|
|
|
2''-dGTP + IMP + L-aspartate <=> 2''-dGDP + phosphate + adenylosuccinate
|
6.3.4.4
adenylosuccinate synthase
|
–
|
|
|
BRENDA:
BS369154
|
|
|
|
ITP + IMP + L-aspartate <=> IDP + phosphate + adenylosuccinate
|
6.3.4.4
adenylosuccinate synthase
|
–
|
|
|
BRENDA:
BS369156
|
|
|
|
ddGTP + IMP + L-aspartate <=> 2',3'-dideoxy-GDP + phosphate + adenylosuccinate
|
6.3.4.4
adenylosuccinate synthase
|
–
|
|
|
BRENDA:
BS369155
|
|
|
|
XTP + IMP + L-aspartate <=> XDP + phosphate + adenylosuccinate
|
6.3.4.4
adenylosuccinate synthase
|
–
|
|
|
BRENDA:
BS711
|
|
|
|
inosine_5''-phosphoramidate + H2O <=> IMP + NH3
|
3.6.1.29
bis(5'-adenosyl)-triphosphatase
|
–
|
|
|
BRENDA:
BS405484
|
|
|
|
D-glucose_6-phosphate + Inosine <=> D-glucose + IMP
|
2.7.1.77
nucleoside phosphotransferase
|
–
|
|
|
BRENDA:
BS357915
|
|
|
|
IMP + nicotinamide_hypoxanthine_dinucleotide + H2O <=> H+ + deamino-NADH + XMP
|
1.1.1.205
IMP dehydrogenase
|
–
|
|
|
SABIO-RK:
11155
|
|